Collective term for psychotrope substances with Amphetamine related structure, which possesses only two C-atoms in the site chain instead of three. The Phenethylamines are covered like the Amphetamines by the Misuse of Drugs Act 1971, Schedule 2 part 1. The nomenclature begins therefore with "2C", followed by the substituent in para position (C, B, I for chlorine, bromine, iodine or T for Thioalkyl), and the last number describes the alkyl chain, 1 for methyl, 2 for ethyl, 7 for propyl).
Phenethylamine itself is a natural occuring alkaloid deriving from the amino acid phenylalanine by enzymatic decarboxylation.
Most important representatives are 2C-B, 2C-T-2 and 2C-T-7, which were synthethisiert by the American drug Pope Alexander Shulgin and described in his book "PHIKAL" 1991. In the USA so far 3 cases of deaths by an overdose of 2C-T-7 are known, in particular in connection with Ecstasy consumption. In the EU, Phenethylamines are so far insignificant.
2C-B
4-Bromo-2,5-dimethoxyphenethylamine, 4-Bromo-2,5-dimethoxyphenethylazane, C10H14BrNO2, MW 260,13 g/mol, Scene designation: Venus, Nexus, Bromo
1974 by Shulgin synthesized drug with strongly dose-dependent effect. With smaller dosage (5-15 mg) ecstasy-like effects without hallucinations, with dosages between 15-30 mg halluzinogene effects, similarly LSD or Psilocybin. Occasionally a white powder for sniefing, usually small tablets for the oral admission. The pharmacology is so far unknown. The halluzinogenic effect is from relatively short duration.
