5H-Dibenz[b,f]azepin-5-carboxamide, C15H12N2O, MW 236,26 g/mol
Trade Marks: Tegretol, Teril
Carbamazepine is used for the effective treatment for epilepsy, but also used for the preventing of the avoidance of accumulations with MS and the alcohol withdrawal syndrome. Daily uptake 400-1200 mg after slowly increased dosage to the beginning of therapy. Tablets with 200 mg active substance, retarding tablets with 200, 400 and 600 mg. Adverse Effects: somnolence, sedation, tiredness, ataxias. By overdosage consciousness disturbances up to coma.
Half-life-time 8-24 hours. The dismantling takes place in the liver to the 10,11-carbamazepine epoxide. Interactions with other substances, usually accelerating, among other with psychopharmaca.
Therapeutic blood level: 2-8 µg/ml
