Zopiclone
Zopiclone, (R,S)-6-(5-Chloro-2-pyridyl)-7-oxo-6,7,dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl4-methylpiperazin-1-carboxylate, C17H17ClN6O3, M=388,81 g/mol
Group: Hypnotic (Cyclopyrrolone)
Trade name: Zimovane®
Application
None-Benzodiazepine for short-term treatment of insomnia in cases of clinically meaningful severity. Tablets with 3.75 and 7.5 mg of the racemic mixture
.Contra-Indications
Respiratory failure, liver failure. Do not apply during pregnancy and lactation.
Interactions
Efficiency gain with other CNS-drugs. Alcohol also increases the sedative effect.
Site reactions
Fatigue, reduced response capability
Analysis
Therapeutic blood/plasma level < 0.1 µg/ml zopiclone.
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