German Version

Sertraline (1S,4S)-4-(3,4-Dichlorphenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphtylamine, M=306,23 g/mol

Selective Serotonin Reuptake Inhibitor (SSRI)

Trade Mark: Zoloft®, Gladem®, Lustral®



Treatment of depressive illnes and anxiety.


Do not use with MAO inhibitors, because of the danger of a Serotonine syndrome. Do not use with patients under 18 years of age. Do not use during pregnancy.

Adverse Effects

Especially at the beginning, nausea can occur. When setting off, reduce dose slowly, increased risk of suicides.


The determination of Sertraline can take place after extraction by means of HPLC/DAD. Therapeutic levels: 0.05-0.25 µg/ml.

Overview SSRI

Overview Antidepressiva

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Last modification (M-D-Y): 02/08/2019 - IMPRINT - FAQ