Sildenafil
 
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Sildenafil 1-{[3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperazine, C28H38N6O11S, M=474,58 g/mol

Type: PDE Type 5 Inhibitor)

Trade Names: Viagra®, Revatio®

Viagra

Usage

Sildenafil is used for the treatment of erectile dysfunction and pulmonary arterial hypertonia. Half life 4-6 hours. Effects only after sexual stimulation.

Contra-Indications

Do not use Sildenafil together with nirate containing medicines or other NO donatating agents ( p.e. Poppers)!

Interactions

Effects increased with Cimetidine

Site effects

Headache

Analytics

Therapeutic blood level 0,0005 up to 0,01 µg/ml. Sildenafil is metabolised by hepatic enzymes (N-demethylation) and excreted by both the liver and kidneys.

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Last modification (M-D-Y): 02/08/2019 - IMPRINT - FAQ